Adhesion of Klebsiellapneumoniae to human epithelial cells and influence of protamine

✍ Scribed by R. Traore; P. Boussard; M. Devleeschouwer

• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 560 KB
• Volume: 2
• Category: Article
• ISSN: 0927-7765
• DOI: 10.1016/0927-7765(94)80025-1

✦ Synopsis

BacterIaI adhesion IS an obhgatory step leadmg to colomsatlon of the host. In vitro adhesion of Rlehswlla pneumonrue, at 10' and lo9 bacteria ml-', to buccal cells from three non-smokmg donors showed that at lo9 bacteria ml-' the number of adherent microorgamsms is more statlstlcally slgmficant (p<O.Ol. ANOVA) than at 10' bacteria ml-'. With protamme at a concentration of 100 pg ml I, under our experimental condltlons tlus basic protem abohshed 60% of the adhesion on buccal and urmary cells For urinary cells from one donor, the number of adherent bacteria was generally greater when cells were collected in the second part of the menstrual cycle Key words~ Adhesion: Human buccal epithehal cells; Human urmary eplthehal cells: K/ehs&l~r pnrumon~r, Protamme