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Adhesion of HT-29 colon carcinoma cells to endothelial cells requires sequential events involving E-selectin and integrin β4

✍ Scribed by Julie Laferrière; François Houle; Jacques Huot

Book ID
111577289
Publisher
Springer
Year
2004
Tongue
English
Weight
275 KB
Volume
21
Category
Article
ISSN
0262-0898

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Adhesion of HT-29 colon carcinoma cells
Adhesion of HT-29 colon carcinoma cells to E-selectin results in increased tyrosine phosphorylation and decreased activity of c-src
✍ Sharon A. Soltesz; Elaine A. Powers; Jian-Guo Geng; Chris Fisher 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 266 KB

Adhesion of metastatic cancer cells at secondary sites is known to be regulated by several families of adhesion proteins, including selectins and integrins. Colon carcinoma cells have been shown to tether to and roll on both stimulated endothelial cells and purified E-selectin. We have demonstrated