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Adherence to candesartan and placebo and outcomes in chronic heart failure in the CHARM programme: double-blind, randomised, controlled clinical trial

✍ Scribed by Bradi B Granger; Karl Swedberg; Inger Ekman; Christopher B Granger; Bertil Olofsson; John JV McMurray; Salim Yusuf; Eric L Michelson; Marc A Pfeffer

Book ID
117290591
Publisher
The Lancet
Year
2005
Tongue
English
Weight
124 KB
Volume
366
Category
Article
ISSN
0140-6736

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## Background: Chronic heart failure is associated with high mortality and morbidity. raised resting heart rate is a risk factor for adverse outcomes. we aimed to assess the effect of heart-rate reduction by the selective sinus-node inhibitor ivabradine on outcomes in heart failure. ## Methods: P