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Adenovirus-transduced dendritic cells stimulate cellular immunity to melanoma via a CD4+ T cell-dependent mechanism

✍ Scribed by Steitz, J; Brück, J; Knop, J; Tüting, T

Book ID: 110038979
Publisher: Nature Publishing Group
Year: 2001
Tongue: English
Weight: 160 KB
Volume: 8
Category: Article
ISSN: 0969-7128
DOI: 10.1038/sj.gt.3301521

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## Abstract The basis of the adjuvant effect of IL‐1 on the clonal expansion of Ag‐specific CD4 T cells was measured __in vivo__ using the TCR transgenic T cell adoptive transfer method. Injection ofAg plus IL‐1 caused naive CD4 T cells to proliferate to a greater extent than did injection of Ag al