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Adenovirus serotype 3 utilizes CD80 (B7.1) and CD86 (B7.2) as cellular attachment receptors

✍ Scribed by Joshua J Short; Alexander V Pereboev; Yosuke Kawakami; Chenthamarakshan Vasu; Mark J Holterman; David T Curiel


Book ID
113945872
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
765 KB
Volume
322
Category
Article
ISSN
0042-6822

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Costimulation mediated by costimulatory molecules, such as B7-1 and B7-2, which are ligands for the CD28/cytolytic T lymphocyte associated antigen (CTLA)-4 counter-receptor, plays an important role in the induction of T cell-mediated antitumor immunity. We investigated the expressions of B7-1, B7-2,