## Abstract ## Background The helperโdependent adenovirus (HDAd) vector is less immunogenic and has a larger cloning capacity of up to 37 kb enough to carry the fullโlength dystrophin cDNA. However, high and longโterm expression of dystrophin transduced to mature muscle still remains difficult. On
โฆ LIBER โฆ
Adenovirus-mediated transfer of the neurotrophin-3 gene into skeletal muscle of pmn mice: Therapeutic effects and mechanisms of action
โ Scribed by G Haase; B Pettmann; E Vigne; L Castelnau-Ptakhine; H Schmalbruch; A Kahn
- Book ID
- 118052254
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 431 KB
- Volume
- 160
- Category
- Article
- ISSN
- 0022-510X
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## Abstract Chronic mechanical compression of the spinal cord causes neural tissue damage, including loss of anterior horn cells around the level of injury. Exogenous delivery of neurotrophins to neuronal cells could provide neuroprotection to a spinal cord subjected to mechanical injury. We invest
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