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Adenovirus-Mediated Transfer of Caspase-8 in Combination with Superrepressor of NF-κB Drastically Induced Apoptosis in Gliomas

✍ Scribed by Nobusada Shinoura; Naoki Yamamoto; Yoko Yoshida; Akio Asai; Takaaki Kirino; Hirofumi Hamada


Book ID
115585704
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
510 KB
Volume
271
Category
Article
ISSN
0006-291X

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## Abstract ## Background In order to develop a safe and effective gene therapy for cancer, more powerful therapeutic genes must be selected and a gene transduction methodology needs to be devised that minimizes the total dose of vector required. We investigated the combination effect of 5‐fluorou