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Adenovirus-Mediated p53 Gene Transfer to the Bile Duct by Direct Administration Into the Bile in a Rat Cholangitis Model1

โœ Scribed by Yoh Kojima; Kazuo Honda; Hiroshi Kotegawa; Fumiki Kushihata; Nobuaki Kobayashi; Bingbing Liu; Kazunari K. Yokoyama

Book ID
116701899
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
336 KB
Volume
128
Category
Article
ISSN
0022-4804

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Proliferative cholangitis (PC) associated with hepatolithiasis develops the stricture of main bile ducts, and is the main cause of residual and/or recurrent stones after repeated treatments for hepatolithiasis. The aim of this study was to inhibit PC using the cytostatic gene therapy with direct ade