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Adenovirus-mediated p16/CDKN2 gene transfer suppresses glioma invasion in vitro

✍ Scribed by Chintala, Shravan K; Fueyo, Juan; Gomez-Manzano, Candelaria; Venkaiah, Boyapati; Bjerkvig, Rolf; Yung, WK Alfred; Sawaya, Raymond; Kyritsis, Athanassios P; Rao, Jasti S


Book ID
110060966
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
648 KB
Volume
15
Category
Article
ISSN
0950-9232

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Adenovirus-mediated p16 gene transfer pr
✍ Seiji Hama; Yuji Heike; Ichiro Naruse; Minako Takahashi; Hiroyuki Yoshioka; Kazu πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 157 KB

This study examined the effects of full-length p16 gene transfer by recombinant adenovirus on cell growth and on sensitivity to CDDP or ACNU chemotherapies. We developed a recombinant adenovirus expressing the full-length human p16 gene (AxCA-hp16) by the COS-TPC method. AxCA-hp16 was infected into