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Adenovirus-mediated gene transfer of A20 in murine islets inhibits Fas-induced apoptosis

✍ Scribed by S.T Grey; J Lock; F.H Bach; C Ferran

Book ID
117230202
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
65 KB
Volume
33
Category
Article
ISSN
0041-1345

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## Abstract A20 was originally characterized as a TNF‐inducible gene in human umbilical vein endothelial cells. As an NF‐κB target gene, A20 is also induced in many other cell types by a wide range of stimuli. Expression of A20 has been shown to protect from TNF‐induced apoptosis and also functions