Gene transfer of angiogenic growth factors with replicationdeficient recombinant adenovirus (Ad) vectors may provide a new approach to the treatment of ischemic diseases. To determine if Ad-infected cells could stimulate angiogenesis in vivo and to assess the tumorigenicity of cells infected with th
Adenovirus-Mediated Acidic Fibroblast Growth Factor Gene Transfer Induces Angiogenesis in the Nonischemic Rabbit Heart
β Scribed by Jorge Safi Jr.; Anthony F. DiPaula Jr.; Teresa Riccioni; Jan Kajstura; Giuseppe Ambrosio; Lewis C. Becker; Piero Anversa; Maurizio C. Capogrossi
- Book ID
- 115641053
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 430 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0026-2862
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## Abstract ## Background The present study aimed to determine the efficiency and safety of baculovirusβmediated intravitreal gene transfer in rabbit eye and to compare its efficiency with adenovirus. We also studied how an intravitreal injection of vectors producing vascular endothelial growth fa