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Adenovirus expressing IFN-λ1 (IL-29) attenuates allergic airway inflammation and airway hyperreactivity in experimental asthma

✍ Scribed by Li, Yan; Gao, Qiaoyan; Yuan, Xianli; Zhou, Mi; Peng, Xiao; Liu, Xiaojin; Zheng, Xiaoxuan; Xu, Damo; Li, Mingcai


Book ID
122089426
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
921 KB
Volume
21
Category
Article
ISSN
1567-5769

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## Abstract ## Background Allergic asthma strongly correlates with airway inflammation caused by cytokines secreted by allergen‐specific type‐2 T helper (Th2) cells, but the immunologic regulation of cell function is yet to be acquired. Further, IL‐10 has been found to exert both antiinflammatory