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Adenoviral vector-mediated insulin gene transfer in the mouse pancreas corrects streptozotocin-induced hyperglycemia

✍ Scribed by Shifrin, A L; Auricchio, A; Yu, Q-C; Wilson, J; Raper, S E


Book ID
110039001
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
254 KB
Volume
8
Category
Article
ISSN
0969-7128

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## Abstract ## Background Previous studies demonstrating the efficacy of insulin gene therapy have mostly involved use of adenoviral vectors or naked DNA to deliver the insulin gene. However, this procedure may not guarantee long‐term insulin production. To improve the performance, we prepared rec