## BACKGROUND. Adenosquamous carcinoma (ASCa) is a rare subtype of ductal adenocarcinoma of the pancreas with what to the authors' knowledge are limited cytologic descriptions. In the current study, the authors describe their experience with the fine-aspiration biopsy (FNAB) diagnosis of ASCa and
Adenosquamous carcinoma of the pancreas: preoperative diagnosis and molecular alterations
โ Scribed by Yoshiaki Murakami; Takashi Yokoyama; Yujiro Yokoyama; Tetsuya Kanehiro; Kenichiro Uemura; Masaru Sasaki; Masahiko Morifuji; Taijiro Sueda
- Book ID
- 106179375
- Publisher
- Springer Japan
- Year
- 2003
- Tongue
- English
- Weight
- 239 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0944-1174
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Four cases of adenoacanthoma of the pancreas were collected and the literature reviewed. T h i s uncommon histologic variant appears as aggressive and malignant as the more common adenocarcinomas. Two of these four cases had originally been diagnosed as squamous cell carcinomas and were shown to be
Cellular protooncogenes, tumor suppressor genes (antioncogenes), and DNA mismatch repair mutators are generally the key molecular genetic biomarkers undergoing alterations during carcinogenesis, i.e., activation of oncogenes, inactivation of tumor suppressors, and DNA mismatch repair gene defects ar