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Adenosine receptors and vascular inflammation

✍ Scribed by Dovenia S. Ponnoth; S. Jamal Mustafa


Book ID
116275059
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
524 KB
Volume
1808
Category
Article
ISSN
0005-2736

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A 2A adenosine receptors are expressed on immune cells including neutrophils, lymphocytes, eosinophils, monocytes/macrophages, and mast cells. Activation of A 2A receptors on these cells stimulates an increase in [cyclic AMP] i and causes a diminution of inflammatory responses. In mast cells, degran