Adenosine receptor–dopamine receptor interactions in the basal ganglia and their relevance for brain function
✍ Scribed by Kjell Fuxe; Sergi Ferré; Susanna Genedani; Rafael Franco; Luigi F. Agnati
- Book ID
- 116835294
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 465 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0031-9384
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Behavioral and biochemical studies suggest that a negative interaction exists between adenosine A 1 and dopamine D 1 receptors in the brain and that this may contribute to the psychomotor effects of adenosine receptor agonists and antagonists. We examined the functional significance of A 1 and D 1 r
There is increasing evidence that adenosine (ADO) and dopamine (DA) interact directly in the basal ganglia via actions at ADO A,, and DA D2 receptors, respectively. The purpose of this study was to determine 1) the extent to which these receptors modulate endogenous GABA release in discrete regions