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Adenosine is a negative regulator of NF-κB and MAPK signaling in human intestinal epithelial cells

✍ Scribed by Humberto B. Jijon; John Walker; Frank Hoentjen; Hugo Diaz; Julia Ewaschuk; Christian Jobin; Karen L. Madsen

Book ID: 113526914
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 357 KB
Volume: 237
Category: Article
ISSN: 0008-8749
DOI: 10.1016/j.cellimm.2005.10.005

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## Abstract Butyrate, a short chain fatty acid (SCFA) produced by bacterial fermentation of undigested carbohydrates in the colon, constitutes the major fuel for colonocytes. We have earlier shown the role of apically localized monocarboxylate transporter isoform 1 (MCT1) in transport of butyrate i