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Adenosine inhibits locus coeruleus neurons: An intracellular study in a rat brain slice preparation

✍ Scribed by Sarah A. Shefner; Tsai H. Chiu

Book ID
118871924
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
476 KB
Volume
366
Category
Article
ISSN
0006-8993

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The firing rate of locus coeruleus (LC) neurons in rat brain slices was increased reversibly by agents that either elevate intracellular levels of adenosine 3'3'cyclic monophosphate (CAMP) or mimic its actions (e.g., forskolin, an activator of adenylate cyclase, 8-Br-cAMP, a membrane permeable analo