Adenosine induces ATP release via an inositol 1,4,5-trisphosphate signaling pathway in MDCK cells
β Scribed by Keisuke Migita; Lei Lu; Yumei Zhao; Kenji Honda; Takahiro Iwamoto; Satomi Kita; Takeshi Katsuragi
- Book ID
- 116289950
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 239 KB
- Volume
- 328
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract In nonβexcitable cells, the inositol 1,4,5βtrisphosphate receptor (IP~3~R), a ligandβgated Ca^2+^ channel, plays an important role in the control of intracellular Ca^2+^. There are three subtypes of IP~3~R that are differentially distributed among cell types. AR4β2J cells express almost
We have studied arginine vasopressin (AVP)-, thapsigarginand inositol 1,4,5trisphosphate (InsPJ-mediated CaL+ release in renal epithelial LLC-PK, cells. AVP-induced changes in the intracellular free calcium concentration ([Ca"],) were studied in indo-1 loaded single cells by confocal laser cytometry
## Abstract Recently, ATP has gained much interest as an extracellular messenger involved in the communication of calcium signals between cells. The mechanism of ATP release is, however, still a matter of debate. In the present study we investigated the possible contribution of connexin hemichannel