Adenosine Deaminase and 5′Nucleotidase Activities in Peripheral Blood T Cells of Multiple Sclerosis Patients
✍ Scribed by S. Vivekanandhan; C. C. Soundararajan; M. Tripathi; M. C. Maheshwari
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 167 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0364-3190
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DNAs from peripheral blood mononuclear cells (PBMCs) of 21 patients with multiple sclerosis (MS), 1 patient with tropical spastic paraparesis (TSP) as well as DNAs from brain and spinal cord of 5 MS cases and 3 controls were examined for human T-cell lymphotropic virus (HTLV)-related sequences by po
## Abstract The presence of clonally restricted B lymphocytes in the peripheral blood of patients with multiple sclerosis (MS) was investigated using a cytofluorometric technique able to detect lymphocytes having homogeneous amounts of surface immunoglobulin of one light chain class. Thirty‐five of
## Abstract Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, and it is considered to be a T helper 1 (Th1) cell‐mediated autoimmune disease. T‐bet has been identified as a key transcription factor for the development of Th1 cells and the inducti