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Adenosine A1 receptor antagonists in clinical research and development

✍ Scribed by Hocher, Berthold

Book ID
121872683
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
130 KB
Volume
78
Category
Article
ISSN
0085-2538

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The thienopyridine derivatives (platelet
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**Summary** The thienopyridines, ticlopidine and clopidogrel, are antiplatelet drugs. They are prodrugs and are metabolised in the liver to active metabolites that are non‐competitive antagonists of the platelet adenosine diphosphate receptor, P2Y~12~. Inhibition of platelet aggregation by these dru