Adenosine A1 receptor, a target and regulator of estrogen receptorα action, mediates the proliferative effects of estradiol in breast cancer
✍ Scribed by Lin, Z; Yin, P; Reierstad, S; O'Halloran, M; Coon V, J S; Pearson, E K; Mutlu, G M; Bulun, S E
- Book ID
- 109971188
- Publisher
- Nature Publishing Group
- Year
- 2009
- Tongue
- English
- Weight
- 537 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The cell‐surface glycoprotein KAI1 suppresses tumor growth and metastasis in various animal models. Downregulation of KAI1 has been implicated in the progression of cancer. However, the mechanisms of KAI1 inactivation are poorly understood. This is the first study that investigates expr
With interest I read the article by Christgen et al. that was recently published under the Fast Track heading in the International Journal of Cancer. 1 The major reported findings, nicely summarized in the article's title, are that (a) KAI1/CD82 is downregulated in 77% of human breast carcinomas and
Human epidermal growth factor receptor 2 (HER2) is frequently overexpressed in human breast cancers. It is known to drive tumor growth and progression and represents a prominent target in breast cancer therapy. The endothelin (ET) system, in particular ET-1 and its receptor ET A R, is of major relev