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Adenomatous polyposis coli (Apc) tumor suppressor gene as a multifunctional gene

โœ Scribed by Takao Senda; Atsushi Shimomura; Akiko Iizuka-Kogo

Book ID
109005711
Publisher
Springer Japan
Year
2005
Tongue
English
Weight
411 KB
Volume
80
Category
Article
ISSN
1447-6959

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Mutations of the APC adenomatous polypos
Mutations of the APC adenomatous polyposis coli) gene
โœ Hiroki Nagase; Yusuke Nakamura ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 823 KB

Several investigators have reported germline mutations of the APC gene in patients with familial adenomatous polyposis (FAP) as well as somatic mutations in tumors developed in digestive organs (stomach, pancreas, colon, and rectum). Those results provide evidence that inactivation of the APC gene p