Adenoid cystic carcinoma of the uterine cervix. Report of 4 cases

✍ Scribed by H. Stephen Gallager; C. B. Simpson; Alberto G. Ayala

• Publisher: John Wiley and Sons
• Year: 1971
• Tongue: English
• Weight: 457 KB
• Volume: 27
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197106)27:6<1398::aid-cncr2820270620>3.0.co;2-p

✦ Synopsis

Four new cases of adenoid cystic carcinoma of the cervix are reported and analyzed together with the 6 acceptable previously reported cases. Available data indicate that a typical patient is likely to be an elderly multjgravid Negro woman. The prognosis associated with this lesion is apparently poor. Only one patient is known to have survived 3 years without recurrence. When cribriform arcas are not present in a biopsy, the diagnosis may readily be missed.

CHERTKOFF AND SEDLIS,' I N 1962, FIRST DE-

T scribed an unusual uterine neoplasm which they named "cylindroma of the cervix," because of its histologic similarity to adenoid cystic carcinoma of salivary gland. Five additional cases have subsequently been reported.3-6 Little information, however, is available to indicate the biologic potential of this distinctive neoplasm. Follow-up data covering more than a few months has been recorded for only two patients, both in the series of Grafton et al.4 One died of a cerebral vascular accident, and the other was living 5 years after treatment with recurrent pelvic tumor.

At the University of Texas M. D. Anderson Hospital and Tumor Institute at Houston, 6 examples of cervical adenoid cystic carcinoma were encountered between January 1, 1968 and June 30, 1970. Complete clinical data is available for 4 of these patients.

CASE REPORTS

Case 1. A 68-year-old Negro woman, gravida VIII, para VIII, and 20 years post-menopausal, experienced an onset of vaginal bleeding in December 1966. The uterus was found to be deflected to the right by an enlarged, hard cervix and lower uterine segment, T h e