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Adenocarcinoma of the lung: Electron microscopy of fine-needle aspiration biopsy specimens—a review of 73 cases

✍ Scribed by Cesar V. Reyes; JoAnne D. Jensen; Galen Graham

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
250 KB
Volume
20
Category
Article
ISSN
8755-1039

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✦ Synopsis

During a 10-yr period, 128 consecutive cases of pulmonary adenocarcinoma of varying differentiation were diagnosed with percutaneous fine-needle aspiration biopsy. Sediments from the needle and syringe washings with 3% glutaraldehyde were obtained and processed for electron microscopic evaluation in 73 cases. Our results showed three types of adenocarcinoma: 62 cases of nonciliated bronchiolar cell origin, 6 cases of bronchioloalveolar cell origin, and 3 cases of mucous cell origin. In addition, there was an example of combined adenosquamous carcinoma and an instance of amphicrine carcinoma. Our study provided a more precise definition of the cytologic diagnosis and insight into the heterogeneity of lung adenocarcinoma. However, prognostic differences between cell types of lung adenocarcinoma were not observed.

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