Adenocarcinoma in situ with a small cell (endometrioid) pattern in cervical smears
β Scribed by Lee, Kenneth R.
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 166 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
BACKGROUND.
Papanicolaou smears have been less effective in preventing cervical adenocarcinoma than in preventing squamous carcinoma. One reason may be a lack of awareness of certain smear patterns of adenocarcinoma in situ (AIS) such as those with crowded small cells (endometrioid pattern).
π SIMILAR VOLUMES
BACKGROUND. Some cervical/vaginal Papanicolaou (Pap) smears previously diagnosed as normal in women with a high grade squamous intraepithelial lesion (HSIL) are found to contain abnormal cells on retrospective review. This study characterized and quantitated such cells in 100 Pap smears. ## METHODS
## Background: Immunoreactivity for chromogranin a (cg a) is associated with the presence of neurosecretory granules in tumor cells, but immunohistochemical staining for cg a may be absent in small cell lung carcinoma (sclc), which has only a few secretory granules. localization of cg a mrna is a u
W e read with great interest the article by Sumiyoshi et al., 1 in which the authors report that the detection of chromogranin A (Cg A) mRNA using a new in situ hybridization method is far more sensitive than immunohistochemistry. In their series, 100% of 20 small cell carcinoma (SCLC) cases were po