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Adenocarcinoma following ileal pouch–anal anastomosis for ulcerative colitis: Review of 26 cases

✍ Scribed by Bernardino C. Branco; David B. Sachar; Tomas M. Heimann; Umut Sarpel; Noam Harpaz; Adrian J. Greenstein

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 87 KB
Volume: 15
Category: Article
ISSN: 1078-0998
DOI: 10.1002/ibd.20609

No coin nor oath required. For personal study only.

✦ Synopsis

The occurrence of adenocarcinoma following ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC) is an infrequent and but potentially lethal complication. We have seen 1 such case among 520 IPAAs performed in our group practice between 1978 and February 2008. We have added this case to a review of 25 previously reported cases of adenocarcinoma of the pouch or outflow tract following IPAA for UC. Our conclusions are 1) that post-IPAA cancer can occur following either mucosectomy or stapled anastomosis; 2) that this malignancy can occur after IPAA performed for UC either with or without neoplasia; and 3) that this complication is seen whether or not the initial cancer or dysplasia had involved the rectum.

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