## Abstract ## Background Mucopolysaccharidosis VI (MPS VI), due to recessively inherited 4βsulfatase (4S) deficiency, results in lysosomal storage of dermatan sulfate in numerous tissues. Retinal involvement is limited to the retinal pigment epithelium (RPE). This study aimed to determine whether
β¦ LIBER β¦
Adeno-associated virus vector-mediated delivery of pigment epithelium-derived factor restricts neuroblastoma angiogenesis and growth
β Scribed by Christian J. Streck; Youbin Zhang; Junfang Zhou; Catherine Ng; Amit C. Nathwani; Andrew M. Davidoff
- Book ID
- 116684922
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 421 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0022-3468
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## Abstract ## Background We previously demonstrated that a new lentiviral vector derived from nonpathogenic simian immunodeficiency virus (SIVagm) was efficient and safe for longβlasting retinal gene transfer, and that it provided the significant therapeutic effect of expressing human pigment epi