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Adeno-associated viral vectors as agents for gene delivery: application in disorders and trauma of the central nervous system

✍ Scribed by Marc J Ruitenberg; Ruben Eggers; Gerard J Boer; Joost Verhaagen

Book ID: 117702154
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 842 KB
Volume: 28
Category: Article
ISSN: 1046-2023
DOI: 10.1016/s1046-2023(02)00222-0

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## Abstract ## Background Finding efficient central nervous system (CNS) delivery approaches has been the major challenge facing therapeutic development for treating diseases with global neurological manifestation, such as mucopolysaccharidosis (MPS) IIIB, a lysosomal storage disease, caused by au