## CYTOSINE METHYLATION IN GENE REGULATION Current evidence on the role of cytosine methylation in the DNA of eukaryotes suggests that methylation plays a role in stabilizing inactive chromatin domains. The existence of proteins that bind specifically to methylated DNA suggests that folded (conden
Adenine Methylation in Eukaryotic DNA
โ Scribed by B. F. Vanyushin
- Book ID
- 106457129
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2005
- Tongue
- English
- Weight
- 105 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0026-8933
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DNA methylation is catalyzed by a family of conserved DNA methyltransferases and is widespread among protists, plants, fungi and animals. It is however absent in some species and its genomic distribution varies among organisms. Sequence comparisons suggest that known and putative eukaryotic DNA meth
A previous Working Hypothesis on the role of DNA methylation in eukaryotic stability presented enzymological data suggesting the DNA methylation has evolved as a biological response to the formation of unusual DNA structures. . That evidence suggested that human DNA methyltransferase is uniquely sui