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Adducts of 2-aminothiophenol with acetylenic nitriles or esters and their conversion into benzothiazoles and/or 1,4-benzothiazines

✍ Scribed by Gaetano Liso; Giuseppe Trapani; Vincenza Berardi; Andrea Latrofa; Paolo Marchini


Book ID
112126049
Publisher
Journal of Heterocyclic Chemistry
Year
1980
Tongue
English
Weight
235 KB
Volume
17
Category
Article
ISSN
0022-152X

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Oxazepines and thiazepines. 41 . Synthes
✍ Albert Lévai 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 157 KB

## Abstract New 4‐aryl‐2,3‐dihydro‐2‐styryl‐1,5‐benzothiazepines **8–13** have been synthesized by an acid catalyzed reaction of 2‐arninothiophenol (**1**) and (__E,E__)‐cinnamylideneacetophenones **2–7.** Ring contraction of 1,5‐benzothiazepines **8–13** provided 2,2‐disubstituted 3‐acetyl‐2,3‐dih