✦ LIBER ✦

Additive/synergistic interaction between MKP-1 inhibitors and anti-cancer drugs in human non-small-cell lung cancer cell H292

Book ID: 117659701
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 155 KB
Volume: 38
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(02)81010-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

PED interacts with Rac1 and regulates ce

PED interacts with Rac1 and regulates cell migration/invasion processes in human non-small cell lung cancer cells

✍ Ciro Zanca; Flora Cozzolino; Cristina Quintavalle; Stefania Di Costanzo; Lucia R 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 363 KB

## Abstract PED (phosphoprotein enriched in diabetes) is a 15 kDa protein involved in many cellular pathways and human diseases including type II diabetes and cancer. We recently reported that PED is overexpressed in human cancers and mediates resistance to induced apoptosis. To better understand i

Efficacy of Signal Pathway Inhibitors Al

Efficacy of Signal Pathway Inhibitors Alone and in Combination With Cisplatin Varies Between Human Non-Small Cell Lung Cancer Lines

✍ Arman Kilic; Matthew J. Schuchert; James D. Luketich; Rodney J. Landreneau; Tala 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 248 KB

Transactivation of hsp70-1/2 in geldanam

Transactivation of hsp70-1/2 in geldanamycin-treated human non-small cell lung cancer H460 cells: Involvement of intracellular calcium and protein kinase C

✍ Chih-Wen Shu; Nai-Lin Cheng; Whei-meih Chang; Tzu-Ling Tseng; Yiu-Kay Lai 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 330 KB 👁 1 views

## Abstract Geldanamycin is an antitumor drug that binds HSP90 and induces a wide range of heat shock proteins, including HSP70s. In this study we report that the induction of HSP70s is dose‐dependent in geldanamycin‐treated human non‐small cell lung cancer H460 cells. Analysis of the induction of

Relationship between skin rash and outco

Relationship between skin rash and outcome in non-small-cell lung cancer patients treated with anti-EGFR tyrosine kinase inhibitors: A literature-based meta-analysis of 24 trials

✍ Petrelli, Fausto; Borgonovo, Karen; Cabiddu, Mary; Lonati, Veronica; Barni, Sand 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 521 KB

Involvement of calcium in the differenti

Involvement of calcium in the differential induction of heat shock protein 70 by heat shock protein 90 inhibitors, geldanamycin and radicicol, in human non-small cell lung cancer H460 cells

✍ Yuo-Sheng Chang; Lee-Chen Lee; Fang-Chun Sun; Chih-Chung Chao; Hua-Wen Fu; Yiu-K 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 269 KB 👁 2 views

Both geldanamycin (GA) and radicicol (RA) are HSP90 binding agents that possess antitumour activities. Although the in vitro data indicated that the inhibitory constant of RA is much bigger than that of GA, the in vivo data on drug efficacy might reveal different results. We have recently shown that

The selenium analog of the chemopreventi

The selenium analog of the chemopreventive compound S,S′-(1,4-phenylenebis[1,2-ethanediyl])bisisothiourea is a remarkable inducer of apoptosis and inhibitor of cell growth in human non-small cell lung cancer

✍ Arunangshu Das; James Bortner; Dhimant Desai; Shantu Amin; Karam El-Bayoumy 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 749 KB