1972 [5]. Cytogenetic studies have revealed a reciprocal t(9;22)(q22;q12) in the myxoid variant that is characteristic of this tumor and confirm that EMC is a unique entity [6]. Myxoid chondrosarcoma has a broad morphologic spectrum, recently reviewed by Meis-Kindblom et al. [3]. Although, EMC has b
Additive therapy in the maintenance of remission in acute lymphoblastic leukemia of childhood: The effect of the initial leukocyte count
β Scribed by Denis R. Miller; Marilyn Sonley; Myron Karon; Norman Breslow; Denman Hammond
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 760 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0008-543X
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Five weekly doses of triple intrathecal (IT) chemotherapy (methotrexate, hydrocortisone, cytosine arabinoside) starting on day 1 of treatment were added to systemic induction therapy in a regimen (Arm 3) that was compared to three other regimens (Arms 1, 2, and 4) in which central nervous system (CN
## Abstract ## Background Tromboembolic and hemorrhagic complications are significant causes of death in patients with malignancy. These are wellβknown with the use of certain drugs. This study was planned to investigate whether there was any effect of highβdose methotrexate on the hemostatic syst