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Additive myocardial depressant effects of cocaine and ethanol

✍ Scribed by Ronald T. Uszenski; Richard A. Gillis; Gary L. Schaer; Ali R. Analouei; Frederick E. Kuhn


Book ID
115659673
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
867 KB
Volume
124
Category
Article
ISSN
1097-6744

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A Geller-Seifter paradigm for discerning anxiolytic and ataxic effects of drugs was used to study the interactions between low doses of ethanol and cocaine. Ethanol produced significant anxiolytic and ataxic effects at a dose of 1 g/kg. Cocaine at a dose as low as 10 mg/kg markedly antagonized the a