Statin therapy may target both hypercholesterolemia and cholestasis in primary biliary cirrhosis (PBC). However, little is known about the efficacy and safety of statins in PBC. The aim of this single-center study was therefore to prospectively examine the effects of atorvastatin on serum markers of
Additive improvement induced by bezafibrate in patients with primary biliary cirrhosis showing refractory response to ursodeoxycholic acid
β Scribed by Yasuto Takeuchi; Fusao Ikeda; Shin-ichi Fujioka; Toshiyuki Takaki; Toshiya Osawa; Tetsuya Yasunaka; Yasuhiro Miyake; Akinobu Takaki; Yoshiaki Iwasaki; Haruhiko Kobashi; Kazuhide Yamamoto; Tatsuya Itoshima
- Book ID
- 108954145
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 928 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0815-9319
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π SIMILAR VOLUMES
We describe a detailed study of the effects of ursodeoxycholic acid administration on bile acid composition of the serum and bile of patients with primary biliary cirrhosis. Gas chromatography-mass spectrometry was used to analyze bile acids from 10 patients with primary biliary cirrhosis before and
Ursodeoxycholic acid (UDCA) is a safe and effective medical therapy for most patients with primary biliary cirrhosis (PBC). However, some patients show an incomplete response to UDCA therapy. Treatment with corticosteroids may be of benefit although at the expense of systemic side effects. Budesonid
rum. 1 In the past decade, two treatment modalities have Approximately 5% to 10% of patients with features otherbeen shown to be effective in the treatment for PBC, dewise consistent with primary biliary cirrhosis (PBC) lack antipending on the stage of the disease. For patients with less mitochondri