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Additive effect of glial cell line-derived neurotrophic factor and neurotrophin-4/5 on rat fetal nigral explant cultures

✍ Scribed by M Meyer; E.R Matarredona; R.W Seiler; J Zimmer; H.R Widmer


Book ID
117490290
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
1015 KB
Volume
108
Category
Article
ISSN
0306-4522

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Parkinson's disease is characterized by the progressive degeneration of midbrain dopaminergic neurons. Several studies have examined the effects of the dopaminergic neurotrophins growth/differentiation factor 5 (GDF5) and glial cell line-derived neurotrophic factor (GDNF) on these neurons in vitro.

Effect of glial cell line-derived neurot