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Additive effect of Apo2L/TRAIL and Adeno-p53 in the induction of apoptosis in myeloma cell lines

✍ Scribed by Qun Liu; Wafik S El-Deiry; Yair Gazitt


Book ID
114216673
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
200 KB
Volume
29
Category
Article
ISSN
0301-472X

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TRAIL/Apo-2L, a novel cytokine, is a member of the tumor necrosis factor (TNF) family and serves as an extracellular signal triggering apoptosis. TRAIL/Apo-2L is capable of killing various transformed cells but not unstimulated primary T cells. In this study, five human glioma cells (U87, U118, U178