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Additions and Corrections: Corticosteroid Intermediates. IV. Synthesis of 11-Oxygenated Steroids from Ergosterol.

✍ Scribed by Laubach, G; Schreiber, E; Agnello, E; Brunings, K


Book ID
127021093
Publisher
American Chemical Society
Year
1957
Tongue
English
Weight
132 KB
Volume
79
Category
Article
ISSN
0002-7863

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## Abstract The addition of (trimethylsilyl)propargylmagnesium bromide (9) to aldehydes afforded predominantly the allenylic alcohols __rac__‐10. The regioselectivity of this addition changes dramatically when organocerium reagents were used for the addition. In this case nearly exclusive formation