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Additions and Corrections - An Enantioselective Total Synthesis of (-)·Talaromycins A and B.

✍ Scribed by Smith, III, Amos; Thompson, Andrew


Book ID
126083449
Publisher
American Chemical Society
Year
1985
Tongue
English
Weight
67 KB
Volume
50
Category
Article
ISSN
0022-3263

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An enantiospecific synthesis of (−)-tala
✍ Isidoro Izquierdo Cubero; Maria T. Plaza Lo´pez-Espinosa 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 833 KB

3R,4R,5S,6R,9RS)-9-Ethyl-3,4,5-trihydroxy-l,7-dioxaspiro[5.5]undecane (9) has been synthesised from 2,3:4,5-di-0-isopropylidene-/I-D-fructopyranose (3) and transformed into (-)-talaromycin A (1). (-)-Talaromycin B (2) was obtained by isomerisation of 1 in acid medium. \* Dedicated to Professor Lesli