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Addition of estramustine to chemotherapy and survival of patients with castration-refractory prostate cancer: a meta-analysis of individual patient data

✍ Scribed by Karim Fizazi; Aurelie Le Maitre; Gary Hudes; William R Berry; W Kevin Kelly; Jean-Christophe Eymard; Christopher J Logothetis; Jean-Pierre Pignon; Stefan Michiels

Book ID
117784465
Publisher
The Lancet
Year
2007
Tongue
English
Weight
175 KB
Volume
8
Category
Article
ISSN
1470-2045

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## Abstract ## BACKGROUND Combinations of cytotoxic chemotherapy with estramustine phosphate (EMP), a nornitrogen mustard‐estrogen conjugate, are used to treat patients with hormone‐refractory prostate carcinoma (HRPC). However, thromboembolic events (TE), including deep venous thrombosis (DVT), p