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Addition of amino acid moieties to lapatinib increases the anti-cancer effect via amino acid transporters

โœ Scribed by Maeng, Han-Joo; Kim, Eun-Seo; Chough, Chieyeon; Joung, Misuk; Lim, Jee Woong; Shim, Chang-Koo; Shim, Won-Sik


Book ID
125492699
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
502 KB
Volume
35
Category
Article
ISSN
0142-2782

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โœ L. L. Wearley; K. Tojo; Y. W. Chien ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 653 KB

The objective of this investigation was to quantitate the effect of binding on the iontophoretic transport of a series of amino acids. The diffusivity and concentration in the stratum corneum and viable skin were estimated from the passive permeation profiles through whole and stripped skin. Using t