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Addendum to synthesis of some 2-oxo-4-aryl-5-carbethozy-6-trifluoromethyl-1,2,3,4-tetrahydropyrimidines

Publisher: Elsevier Science
Year: 1955
Tongue: English
Weight: 36 KB
Volume: 259
Category: Article
ISSN: 0016-0032
DOI: 10.1016/0016-0032(55)90842-5

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✦ Synopsis

Further proof of structure of 2-oxo-4-(3,4-diethoxyphenyl)-5-carbethoxy-6-trifluoromethyl-l,2,3,4-tetrahydropyrimidine was obtained by comparison of the infrared spectrum* of the compound with that of the 6-methyl analog. The spectra are identical except that a strong band for the C-F bond was found at 8.23 and 8.41 microns in the trifluoromethyl derivative.

More extensive investigation of the ultraviolet absorption spectra of the two compounds indicated the presence of a second absorption peak at 233 millimicrons (density 0.823) for the trifluoromethyl derivative. This may indicate that the compound exists in the enol form in absolute ethanol.

These comparisons of the infrared spectra and of the ultraviolet spectra furnish substantiation of the structure of this trifluoromethyl derivative.

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