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Adaptive Two Stage Designs and the Conditional Error Function

✍ Scribed by Martin Posch; Peter Bauer

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
156 KB
Volume
41
Category
Article
ISSN
0323-3847

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πŸ“œ SIMILAR VOLUMES

SOME OPTIMAL AND NON-OPTIMAL TWO-STAGE D
SOME OPTIMAL AND NON-OPTIMAL TWO-STAGE DESIGNS USING AN Ξ±-SPENDING FUNCTION
✍ H. I. PATEL πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 465 KB

While designing a group sequential clinical trial in the pharmaceutical industry setting, we often face a problem of determining the time for an interim analysis. For a two-stage trial we compute the sample sizes n and N per treatment group for the interim and final analyses. respectively, that mini