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Adaptive Steered Molecular Dynamics: Unfolding of Neuropeptide Y and Decaalanine Stretching

✍ Scribed by Ozer, Gungor; Quirk, Stephen; Hernandez, Rigoberto


Book ID
122164194
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
67 KB
Volume
100
Category
Article
ISSN
0006-3495

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Steered molecular dynamics (SMD), a computer simulation method for studying force-induced reactions in biopolymers, has been applied to investigate the response of protein domains to stretching apart of their terminal ends. The simulations mimic atomic force microscopy and optical tweezer experiment