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Adaptive response to alkylating agents in the Drosophila sex-linked recessive lethal assay

โœ Scribed by Nataliya Savina; Olga Dalivelya; Tatyana Kuzhir


Book ID
117767089
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
204 KB
Volume
535
Category
Article
ISSN
1383-5718

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Nitroguanidine (NG) and its degradation product nitrosoguanidine (NSG) were evaluated for their mutagenic potential by using Drosophila melanogaster sex-linked recessive lethal (SLRL) assay. Following 72 h of feeding exposure, NG and NSG at concentrations of 4-8 pg ml-' and 15-20 mg ml-I, respective