Adaptive mechanisms of the cardiovascular system in transgenic mice – lessons from eNOS and myoglobin knockout mice

System issues: The genetic analysis of l

System issues: The genetic analysis of lacl mutations in sectored plaques from Big Blue® transgenic mice

✍ Gregory R. Stuart; Nancy J. Gorelick; Julie L. Andrews; Johan G. de Boer; Barry 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 761 KB

However, the interpretation of data from transgenic animal assays is sometimes complicated by mutants that appear as sectored mutant lambda plaques. These mutants can form a significant fraction of the mutant plaques [Hayward et al. (1 995): Carcinogenesis 16:2429-24331. Thus, in order to accurately