✦ LIBER ✦

Adaptive Evolution of Scorpion Sodium Channel Toxins

✍ Scribed by Shunyi Zhu; Frank Bosmans; Jan Tytgat

Publisher: Springer
Year: 2004
Tongue: English
Weight: 416 KB
Volume: 58
Category: Article
ISSN: 0022-2844
DOI: 10.1007/s00239-003-2534-2

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inactivated state dependence of sodium c

Inactivated state dependence of sodium channel modulation by β-scorpion toxin

✍ Robert G. Tsushima; Adolfo Borges; P. H. Backx 📂 Article 📅 1999 🏛 Springer 🌐 English ⚖ 154 KB

Unique interaction of scorpion toxins wi

Unique interaction of scorpion toxins with the hERG channel

✍ Yuliya V. Korolkova; Gea-Ny Tseng; Eugene V. Grishin 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 344 KB

## Abstract ERG potassium channels specify one component of the delayed rectifier in the heart and are likely to play an important functional role in other excitable cells. Compared to other K^+^ channels, the human ERG (hERG) channel possesses an unusually long S5‐P linker that presumably forms an

Insect background sodium channel as a ne

Insect background sodium channel as a new target for scorpion alpha toxin

✍ Stankiewicz, Maria; Grolleau, Françoise; Rochat, Hervé; Zlotkin, Eliahu; Pelhate 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB

The effects of an anti-insect scorpion alpha toxin, LqhaIT, isolated from the venom of the Israeli scorpion Leiurus quinquestriatus hebraeus was studied on isolated adult dorsal unpaired median (DUM) neurones isolated from the cockroach Periplaneta americana terminal abdominal ganglion. Using the ce

Classification of Na channel receptors s

Classification of Na channel receptors specific for various scorpion toxins

✍ Kenneth P. Wheeler; Dean D. Watt; Michel Lazdunski 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 355 KB

First chemical synthesis of a scorpion α

First chemical synthesis of a scorpion α-toxin affecting sodium channels: The Aah I toxin of Androctonus australis hector

✍ Sarrah M'Barek; Ziad Fajloun; Sandrine Cestèle; Christiane Devaux; Pascal Mansue 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB

## Abstract Aah I is a 63‐residue α‐toxin isolated from the venom of the __Buthidae__ scorpion __Androctonus australis hector__, which is considered to be the most dangerous species. We report here the first chemical synthesis of Aah I by the solid‐phase method, using a Fmoc strategy. The synthetic

Solution structure of potassium channel-

Solution structure of potassium channel-inhibiting scorpion toxin Lq2

✍ Jean-Guillaume Renisio; Zhe Lu; Eric Blanc; Weili Jin; John H. Lewis; Olivier Bo 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 653 KB

Lq2 is a unique scorpion toxin. Acting from the extracellular side, Lq2 blocks the ion conduction pore in not only the voltage-and Ca 2؉ -activated channels, but also the inward-rectifier K ؉ channels. This finding argues that the threedimensional structures of the pores in these K ؉ channels are si