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Adaptation to jejunoileal bypass promotes experimental colorectal carcinogenesis

✍ Scribed by J. B. Bristol; M. Wells; Professor R. C. N. Williamson

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
641 KB
Volume
71
Category
Article
ISSN
0007-1323

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## Abstract Methylation of the __MLH1__ promoter region has been suggested to be a principal mechanism of gene inactivation in sporadic microsatellite instability (MSI)–positive colorectal carcinoma. Recently, we have shown a novel methylation profile of the __MLH1__ promoter region (i.e., full, pa