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Acylations with the Acid Chloride and Anhydride of 1-n-Butyl-2,5-dimethylpyrrole-3,4-dicarboxylic Acid

✍ Scribed by NIGHTINGALE, DOROTHY V.; GALLAGHER, JAMES A.


Book ID
121286821
Publisher
American Chemical Society
Year
1959
Tongue
English
Weight
558 KB
Volume
24
Category
Article
ISSN
0022-3263

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Friedel-crafts reactions of 2-amino-4-(a
✍ Belew Mekonnen; George Crank πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 484 KB

## Abstract Acid chlorides and anhydrides react with 2‐amino‐4‐alkyloxazoles in the presence of aluminum chloride to produce 5‐acyl substituted 2‐amino‐4‐alkyloxazoles in modest yields. However, in the absence of the Lewis acid reaction occurs at the amino group to give the corresponding amides. Th