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Acylations with Long-Chain Acid Anhydrides and Acyl Chlorides over Zeolite Beta

✍ Scribed by M. Bejblová; D. Procházková; J. Vlk

Publisher
Springer
Year
2008
Tongue
English
Weight
450 KB
Volume
52
Category
Article
ISSN
1022-5528

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Friedel-crafts reactions of 2-amino-4-(alkyl or aryl)oxazoles with acid chlorides and acid anhydrides: Synthesis of 5-acyl-2-amino-4-alkyloxazoles
✍ Belew Mekonnen; George Crank 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 484 KB

## Abstract Acid chlorides and anhydrides react with 2‐amino‐4‐alkyloxazoles in the presence of aluminum chloride to produce 5‐acyl substituted 2‐amino‐4‐alkyloxazoles in modest yields. However, in the absence of the Lewis acid reaction occurs at the amino group to give the corresponding amides. Th